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Biosensor Device and Therapeutics Lab

​News:  Our research paper, "High-affinity one-step aptamer selection using a non-fouling porous hydrogel," has been published in the prestigious journal Nature Biotechnology, an impact factor of 68.20. Our work has garnered significant attention and recognition, with coverage by multiple esteemed news outlets, including Science dailyTechnology networkNanoworkEureka alertMirage and Phy Org.
 
  • We are looking for a suitable candidate for the Junior Research Fellowship (JRF) position at IIT Delhi—eligibility master’s in biomedical/biotechnology/chemical or any other relevant branch with GATE qualification. Please send your CV to nks@cbme.iitd.ac.in.  The shortlisted candidates will be informed of the online/offline interview schedule.
     (Note: Interviews will be conducted as and when a sufficient no. of applications are received)
   
Naveen Singh.png

Naveen Singh.

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About

We approach advanced and innovative techniques in solving critical and emerging issues in diagnostics and therapeutics, signature sensing, pathogen detection, and trace detection. We are developing devices capable of detecting electrophysical and electrochemical responses, potentially providing stimuli-responsive drug delivery. We are involved with all aspects of advanced sensors using a combination of biomaterials, nanomaterials, and electronics with forward-looking engineering efforts.

Education & Experience

Education

WHAT I’VE LEARNED

2013–2019

Ph.D. Indian Institute of Technology Guwahati, India: Department of Biosciences and Bioengineering. (CPGA 8.75/10)

Thesis title: Development of Aptasensor for malaria diagnosis by using Plasmodium falciparum Glutamate dehydrogenase as target antigen (linked)

2011–2013

M.Tech. Birla Institute of Technology and Sciences, Pilani. India, Department of Biological Sciences. (CGPA 7.97/10)

Thesis title: Expression, Purification and Stabilization of human mature lysyl oxidase and lysyl oxidase propeptide.

Experience

WHERE I’VE WORKED

Jan. 2019– Dec 2022

Post-Doctoral Research Staff:Department of Electrical and Computer Engineering, University of California San Diego

May 2017–Dec 2017
Visiting Research Scholar: University of Bath
United Kingdom, Department of Electrical and Electronics
June 2021–Aug 2021
Micro-MBA: Rady School of Management, University of California, San Diego
2007–2011

B. Tech. Allahabad Agriculture University, India. Department of Biotechnology. (CGPA 8.81/10)

Thesis title: Production of alcohol through Barley, Grain and Molasses

Gradient

Skills & Languages

WHAT I BRING TO THE TABLE

Biosensing Techniques

Optical sensors: Colorimetric, fluorescence-based, preparation of nanomaterials, conjugation of biomolecules with nanomaterials. Fabrication of Ubent fiber optic probes, their modification with nanomaterials, Smartphone integration with an optical sensing probe.

Electrochemical sensors: Faradic and Nonfaradic methods, Electrode functionalization with biomolecules and nanomaterials, voltammetric and amperometric measurement techniques, capacitor and field effect transistor based sensor

Paper-based sensor: paper-based microfluidics, fluidics and surface modifications.

Molecular biology and protein expression techniques

Genomics: Nucleic acid isolation and purification (DNA/RNA), Polymerase chain reaction, Primer designing, cloning techniques, Electrophoresis, Real Time PCR, Reverse transcriptase PCR, cDNA synthesis.

Proteomics: Protein expression, purification and characterizations with various techniques, Affinity Chromatography, Dialysis, Enzyme Activity Assay, Sedimentation velocity experiment, western blot, Electrophoresis.

Advanced technique: SELEX (Systematic evolution of ligands by exponential enrichment), high resolution melting PCR, electrophoretic mobility shift assay, ELISA, Binding affinity analysis, ESI and MALDI mass spectroscopy.

Bioinformatics

Genome-wide identification of gene families in genome sequenced species, Gene annotation, Protein structure prediction, Molecular docking, Bioinformatics related online servers use (Expasy, Pfam, Genscan, Blast, Clustal, Mfold, Patchdock etc),

Analytical Techniques

Dynamic light scattering, Circular dichroism, Surface plasmon resonance, Analytical ultracentrifugation, Affinity chromatography, UV-Vis and fluorescence spectroscopy, FTIR and Raman spectroscopy, Microscopy.

Miscellaneous

Mosquito Rearing, Mosquito Dissection, Animal (Swiss albino mice) Handling, Cell line maintains, Cell viability and toxicity assays, Various biochemical/chemical assays, Photolithography and wax printing for paper microfluidics.

English

Hindi

Skills & Languages
Awards & Interests

Awards

WHERE I SHINE

Xprize Rapid COVID testing kit (2020)Registered as a team  (Naveen K Singh, Drew Hall, Partha Ray, E Spencer) with product name PanDemiX, shortlisted as Semi-finalist.

 

Received Rapid Acceleration of Diagnostics (RADx)- grant from National Institutes of Health (NIH) (July 2020- till now).Received Work package 0 and 1 from NIH, applied as team under Prof Drew Hall as principle investigator.  Team members: Naveen K Singh, Partha Ray, Eliah Aronoff-Spencer and Drew Hall (principle investigator).

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Newton-Bhabha PhD Fellowship (2017)Organized by British council and Department of Biotechnology, under part of PhD research work carried out at University of Bath, United Kingdom for 6 months under the supervision of Dr. Pedro Estrela.

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North East Bio start talent search contest (2018)- Received Third prize with prize money Rs 20,000, conducted by Guwahati Biotech Park.

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Shastri-Indo Canadian International Conference (2018)- Received travel grant for Conference held in New Delhi, 7-8 July 2018.

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DST Nano Postdoc Research associate fellowship (2019)-from Govt. of India, selected from across the India for research based on innovation in proposal.  

 

DBT Postdoc Research associate fellowship (2019)- from Govt. of India, selected from across the India for research based on innovation in proposal.  

 

Received best poster award in Conference on Advancement in Science and Technology (ICAST-2018)- organized by JSPS society, Japan at Visva-Bharati, Santiniketan-731235, West Bengal, India.

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Biotechnology Ignition Grant-13 (2018)- Selected till final round of Expert selection committee screening in Biotechnology ignition grant, BIG-13 organised by BIRAC India.

GATE 2011- Percentile: 90.8 Graduate Aptitude Test in Engineering in Life Science, conducted by Ministry of Human Resource  and Development, Govt. of India

Excellent reviewer award-2021- by Journal of Pharmaceutical research International

Certifications

  • BITS Pilani - Teaching Assistant Certification

  • Sexual Violence and Sexual Harassment Prevention – UCSD

  • Biological Laboratory Safety (UCSD)

  • Cyber security and Awareness (UCSD)

  • Ethical values and scientific conduct (UCSD)

  • Lab safety and Lab Hazards training (UCSD)

  • Biomedical Responsible Conduct of Research (UCSD)

Invited Talk

  1. Invited talk at ISPE San Diego (UCSD) and University of California return to learn program, on point of care sensor for COVID detection.

  2. Invited talk at the Molecular Medicine Youth Forum at Hangzhou Medical University.

  3. Invited talk at the Biological Society, BITS Pilani

  4. Member of various scientific community and University level cultural board.

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